{"id":2066,"date":"2025-11-04T14:10:50","date_gmt":"2025-11-04T13:10:50","guid":{"rendered":"https:\/\/nsgh.nl\/?page_id=2066"},"modified":"2025-11-13T11:20:23","modified_gmt":"2025-11-13T10:20:23","slug":"marlous-grijsen-2022","status":"publish","type":"page","link":"https:\/\/nsgh.nl\/nl\/otto-kranendonk-fonds\/marlous-grijsen-2022","title":{"rendered":"Knowledge, attitudes and perceptions of leprosy among leprosy-endemic communities in South Sulawesi"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Marlous Grijsen 2022<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Leprosy is a persistent global health problem with more than 200.000 new cases recorded annually, predominantly affecting underserved populations in low- and middle-income countries.&nbsp;Indonesia has the third highest number of people affected by leprosy in the world.&nbsp;People with leprosy are often heavily stigmatized as misconceptions surround the disease, creating a&nbsp;barrier to implement effective healthcare programmes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">One of the main challenges in the clinical management of leprosy are leprosy reactions that may cause nerve damage and lead to disabilities. We are conducting a randomized controlled trial (called MetLep) to evaluate if adjunctive therapy with metformin in addition to standard antibiotic treatment, can prevent or reduce leprosy reactions in patients with multibacillary leprosy.&nbsp;In preparation of this trial, we will perform a&nbsp;community-based knowledge, attitudes and practices (KAP)-survey combined with in-depth interviews and focus group discussions on leprosy and stigma&nbsp;to improve our understanding of the local communities, the socio-health aspects and lived experiences of persons with leprosy and their family members in South Sulawesi.&nbsp;Study outcomes will guide tailored interventions and engagement activities aimed at improving leprosy literacy in the wider community, reducing stigma and optimisizing the implementation and uptake of the MetLep Trial.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Marlous Grijsen 2022 Leprosy is a persistent global health problem with more than 200.000 new cases recorded annually, predominantly affecting underserved populations in low- and middle-income countries.&nbsp;Indonesia has the third highest number of people affected by leprosy in the world.&nbsp;People with leprosy are often heavily stigmatized as misconceptions surround the disease, creating a&nbsp;barrier to implement [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":161,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-2066","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/nsgh.nl\/nl\/wp-json\/wp\/v2\/pages\/2066","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nsgh.nl\/nl\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/nsgh.nl\/nl\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/nsgh.nl\/nl\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/nsgh.nl\/nl\/wp-json\/wp\/v2\/comments?post=2066"}],"version-history":[{"count":0,"href":"https:\/\/nsgh.nl\/nl\/wp-json\/wp\/v2\/pages\/2066\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/nsgh.nl\/nl\/wp-json\/wp\/v2\/pages\/161"}],"wp:attachment":[{"href":"https:\/\/nsgh.nl\/nl\/wp-json\/wp\/v2\/media?parent=2066"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}